GROUP LEADER - MEDICINAL CHEMISTRY

  • Full-time

Company Description

Eurofins, as a fast-moving group of entrepreneur-led businesses, continues to search for Scientific leaders that can support our continued success.

Our mission requires strategic thinking, a fast-paced mindset and deep scientific expertise in several disciplines in particular Medicinal Chemistry, ADME, DMPK, cellular and molecular pharmacology, enzymology, and screening technologies.  This is coupled with an ability to work collaboratively with internal teams and external partners. This individual will bring innovative solutions to medicinal chemistry problems and programs as part of our Integrated Drug Discovery team, DiscoveryOne™.

We are currently seeking an outstanding individual to join our Medicinal Chemistry Team as a Group Leader in Ongar, UK.  She/he will maintain close interactions with key scientists such as biologists and pharmacologists across the Eurofins discovery organization.  Strong people and mentoring skills and the ability to thrive in a team and goal driven, time-sensitive environment are key attributes.

DiscoveryOne™ defines the value of bringing together Eurofins Discovery's full suite of services under one managed program backed by the expertise, services and program management required to support its client's drug discovery projects.

 ABOUT EUROFINS:

 Eurofins Scientific is an international life sciences company, providing a unique range of analytical testing services to clients across multiple industries, to make life and our environment safer, healthier and more sustainable. From the food you eat, to the water you drink, to the medicines you rely on, Eurofins works with the biggest companies in the world to ensure the products they supply are safe, their ingredients are authentic and labelling is accurate. Eurofins believes it is a global leader in food, environmental, pharmaceutical and cosmetics products testing and in Agroscience CRO services. It is also one of the global independent market leaders in certain testing and laboratory services for genomics, discovery pharmacology, forensics, CDMO, advanced material sciences and in the support of clinical studies.

In over just 30 years, Eurofins has grown from one laboratory in Nantes, France to over 47,000 staff across a network of more than 900 independent companies in over 50 countries and operating more than 800 laboratories. Eurofins offers a portfolio of over 200,000 analytical methods to evaluate the safety, identity, composition, authenticity, origin, traceability and purity of biological substances and products, as well as providing innovative clinical diagnostic testing services, as one of the leading global emerging players in specialised clinical diagnostics testing.

In 2019, Eurofins generated total revenues of EUR €4.56 billion, and has been among the best performing stocks in Europe over the past 20 years.

Job Description

  • As a dynamic scientific project and group leader, direct medicinal chemistry functions for one or more client’s drug discovery projects working in concert with internal and external partners in molecular and cellular biology, pharmacology, computational chemistry, ADME, structural biology and other key functions.
  • Developing and directing clear synthetic strategies towards complex molecules using state-of-the-art synthetic methodologies in a time-sensitive manner.
  • To liaise and work with colleagues throughout the global organization to meet company goals
  • To lead a group of scientists in terms of its scientific direction, training and motivation
  • Maintaining a significant level of knowledge of emerging Organic Chemistry and management of laboratory research.
  • Analyze screening data, perform literature reviews, design, propose, and execute medicinal chemistry plans, coordinate chemistry and biology data to support compound progression and project advancement.
  • Utilizing structure-based design principles to impact rational design of molecules.
  • Generating novel, testable hypotheses to enable clear decision making.
  • Provide scientific direction and leadership for medicinal chemistry activities.
  • Independently designing drug-like molecules utilizing current medicinal chemistry knowledge, including property-based optimization, and an understanding of ADME, pharmacokinetics and optimal physicochemical properties.
  • Participate in shaping and implementing strategies that support medicinal chemistry, organic chemistry and DiscoveryOne™ growth.
  • Ensure optimal interaction/communication and provide updates on project status to clients.
  • Conduct performance review of staff and help them set-up and achieve performance goals.
  • Collaborates with one or more teams of synthetic Chemists to maximize efficiency and productivity to meet client’s needs.
  • Actively getting customer feedback and translating it into solutions, improvements and new requirements to enhance overall productivity.
  • Set up customer centric Key Performance Indicators (KPIs) goals to monitor costs, quality, turnaround time, and other pertinent metrics to aid the progress and success of the chemistry operations and client’s projects.

Qualifications

  • PhD in synthetic organic or medicinal chemistry is required, ideally with postdoctoral experience, plus a minimum of 8 years’ experience in the biopharmaceutical industry, with proven track record in medicinal chemistry.
  • Strong leadership skills with excellent interpersonal skills and proven success of drug discovery and managing cross functional discovery teams.
  • Experience as a project leader in the biopharmaceutical industry is strongly preferred.
  • Strong track record of achievement in the synthesis of complex molecules and/or synthetic methodology development, with deep knowledge of modern synthetic and analytical techniques.
  • Proven track record of scientific contributions to projects, including co-inventorship on patents is preferred.  Senior or co-authorship on publications and presentations would be preferred.
  • Scientific creativity, independent thought and decision making ability.
  • Excellent written and verbal communication skills.
  • Excellent problem-solving skills and autonomy with attention to detail.

 

Additional Information

Are you the person we are looking for?  If so, please visit our careers page at https://careers.eurofins.com/uk/ for more information on how to apply, quoting job reference: EID/05/1120. Applicants must be eligible to work in the UK.

The closing date for completed application forms is Friday 10th December 2020.

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