Temporary Research Associate IV / Senior Research Specialist, Immuno-Oncology Research

  • 111 Oyster Point Blvd, South San Francisco, CA 94080, USA
  • Full-time

Company Description

Five Prime Therapeutics, Inc. (NASDAQ: FPRX) is a publicly traded, clinical-stage biotechnology company focused on discovering and developing innovative immuno-oncology protein therapeutics to improve the lives of patients with serious diseases.  We have an industry-leading and differentiated drug discovery platform.  Our comprehensive proprietary libraries of the extracellular proteome, differentiated screening capabilities and protein therapeutic generation and engineering capabilities comprise a unique and powerful IND engine that positions us to discover novel pathways and targets in immuno-oncology and will continue to generate important development programs.  Our success with our drug discovery platform has led to a pipeline that is on track to more than double to five development programs in clinical trials across multiple indications in 2018.  We also have several undisclosed research programs at different points of the target validation and molecule generation phases that have the potential to yield our next wave of development-stage therapeutic biologics.  And we continue to fuel this process at the earliest stages with new screens planned this year.

Five Prime is committed to innovation and outstanding science to develop effective new drugs for the treatment of severe diseases. We value our culture of openness, collaboration and productivity. 

The company is in a strong financial position and has an effective executive team and Board of Directors. Discover more about FivePrime at www.fiveprime.com

Job Description

We are seeking a talented and highly motivated Research Associate IV/Senior Research Specialist (non-PhD) to join our Immuno-Oncology (IO) Research group. This position offers an opportunity to work as part of the larger IO Research team and with other research scientists aimed at discovering and developing novel antitumor agents.


  • Design, optimize, and implement in vitro biophysical and cell-based binding assays as well as immune-relevant cell-based functional assays using standard assay techniques such as flow cytometry, ELISA, and multiplex cytokine assays
  • Independently perform and analyze experiments using isolated primary immune cell populations from humans and rodents and culture ex vivo
  • Culture and engineer cell lines and prepare reagents and test agents as specified in approved protocols
  • Independently analyze data, prepare reports, and communicate experimental results to scientist and in team meetings
  • Coordinate and execute on assigned tasks by interacting with multi-disciplinary teams
  • Maintain and complete documentation of all experimental procedures and data in an electronic laboratory notebook



  • B.S. degree with 6+ years of relevant experience or M.S. in Cell Biology, Immunology, Life Sciences, or related field with a minimum of 3+ years of research experience including basic biology skills
  • Proficiency with in vitro/ex vivo cell-based techniques including isolation of primary immune cell subsets, mammalian cell culture, transfection, cell-based functional assays, multi-color flow cytometry, alphaLISA/ELISA is required
  • Excellent written and interpersonal communication skills, with the ability to interpret and clearly understand SOPs and laboratory procedures
  • Detail-oriented, analytical with excellent problem-solving skills
  • Proven ability to collaborate in a team-oriented environment
  • Diligent, strong growth mindset with a positive “can-do” attitude towards assigned tasks
  • Good planning and organizational skills to meet deadlines


Additional Information

Diversity Statement:

At FivePrime, we believe a diverse workforce drives our success as a company. We are always working to create an environment where different backgrounds and viewpoints are valued and celebrated.

FivePrime is an equal opportunity employer. FivePrime makes employment decisions, including in recruitment and selection, without consideration of race, color, national origin, religion, sex, gender, gender identity or expression, sexual orientation, age, veteran status or disability.

Recruiter Statement:

Five Prime acknowledges that providers may be a valuable resource for identifying and recruiting candidates for employment.  However, we require that all recruiters engage directly with Five Prime’s Talent Acquisition Team and comply with Five Prime’s requirements prior to transmitting any resumes/CVs or introducing any candidates to Five Prime.  Five Prime’s Talent Acquisition Team is the only function within the Company that can enter into contractual relationships with external recruiters and recruiting agencies.   As such, all unsolicited resumes, CVs, anonymous profiles, or candidate information you may submit to employees of Five Prime will become property of Five Prime and Five Prime will have no obligation to pay you or anyone else for the use of such information, including any finder’s, placement, introduction or placement fee.

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