The Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart (Director Prof. Dr. M. Schwab) as part of the Bosch Health Campus is operated by the Robert Bosch Foundation. Since its foundation in 1973, the institute has emerged as Germany's largest and most renowned scientific research unit in the field of clinical pharmacology. Main research activities concentrate on the influence of genetic and non-genetic factors on variability of drug efficacy and their contributions to disease development. The core facility Chemical Analytics and Synthesis is looking for a

Postdoctoral Scientist in Mass Spectrometry-Based Proteomics (m/f/d)

Main focus of the core facility is the development and provision of innovative workflows and methods for mass spectrometric analysis of all types of small molecules and lipids in biological materials. To strengthen our expertise in proteomics we are looking for a highly motivated well-trained postdoc in this field.

• Establishment of workflows for HR-MS based proteomics from different biological matrices
• Establishment of HR-MS based quantification of endogenous proteins and therapeutic proteins (e.g. monoclonal humanized antibodies)
• Analysis of proteomics datasets using biostatistics and bioinformatics
• Supervision of technicians and master or PhD students

• PhD in chemistry, biochemistry, pharmaceutical sciences or a related discipline
• Experience and solid background in proteomics/protein analysis
• Hands on experience in high resolution mass spectrometry (ideally with Orbitrap mass spectrometer)
• Experience in biostatistical analysis of complex data sets
• Interest in personalized medicine and clinical pharmacology
• Excellent English written and oral communication skills

We offer:

• Opportunities to scientifically develop in an interactive team and an exciting scientific environment
• State-of-the-art equipment in analytical instruments and expert knowledge in statistical data analysis within the biostatistical core facility
• The opportunity to collaborate with experts of other professions (e.g. molecular & cell biologists, clinicians)
• The opportunity to communicate scientific results at international conferences and to participate in workshops

For further information, please contact Dr. Ute Hofmann (phone 0711-8101-5907), Dr. Thomas Mürdter (phone 0711-8101-5974), or Prof. Dr. Matthias Schwab (phone 0711-8101-3700).

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