Clinical Variant Scientist, Health and Wellness

  • San Francisco, CA, USA
  • Full-time

Company Description

We’re a cutting-edge tech company with a very human mission—to help every person discover, preserve, and share the story of what led to them. Combining the rich information in family trees and historical records with the genetic details revealed in DNA, we create unique experiences that give people a new understanding of their lives, because connecting all the pieces of our family story can give us the deepest sense of who we are.

Job Description

Ancestry is seeking a Clinical Variant Scientist to join our DNA team. We are mounting a major effort to use genomics to shed light on human diversity, origins, relationships, and human health. This position will focus on ensuring the clinical validity of the interpretation of genetic results for health and wellness.  This position can be based at either our headquarters in Lehi, Utah or our office in San Francisco, California.

The Opportunity

You will be an integral part of a team consisting of population geneticists, epidemiologists, laboratory scientists, and product development specialists generating and communicating impactful insights involving personalized genomics. You will use your skills and experience in human genetics to ensure accuracy and utility of our future products.

What you will do

  • Review, evaluate, and curate literature and public databases
  • Curate, document, and organize candidate markers and conditions or phenotypes
  • Create a consistent process for evaluation of clinical relevance for candidate markers, and apply and document this process for future markers and conditions of interest
  • Contribute your expertise to the development of our future health and wellness products


  • Masters or PhD in human genetics, genetic counseling, or related area with minimum 2 years of relevant experience
  • Previous research or industry experience with evaluating clinical validity, variant curation, or variant interpretation
  • Familiarity with genomic assays such as microarray or next-generation sequencing
  • Demonstrated ability to understand, synthesize, and coherently evaluate complex genetic information as well as related molecular biology
  • Strong written and verbal communication skills
  • Strong organizational skills and attention to detail

Additional Information

Helping people discover their story is at the heart of ours. Ancestry is the largest provider of family history and personal DNA testing, harnessing a powerful combination of information, science and technology to help people discover their family history and stories that were never possible before. Ancestry’s suite of products includes: AncestryDNA, AncestryProGenealogists, Fold3,, Find a Grave,, and Rootsweb.

We offer excellent benefits and a competitive compensation package. For additional information, regarding our benefits and career information, please visit our website at