Computational Biologist (Genomic Data Scientist)

  • San Francisco, CA, USA
  • Full-time

Company Description

When you join Ancestry, you join our family tree. Backed by history, science, and technology, we’re creating a new world of connection, innovation, and understanding. Whether it’s reuniting long-lost relatives through DNA or unearthing new family stories from historical records, Ancestry empowers life-changing experiences. With over 10 billion digitized historical records, 100 million family trees, and 14 million DNA kits sold, Ancestry is bringing the power of personal discovery to people around the world.

Job Description

AncestryDNA is seeking a motivated and talented computer scientist with interest and experience developing computational algorithms to analyze genomic data to infer and characterize shared ancestry and relationships. As a member of the DNA Science team you will be working on cutting edge genomic research that will translate into products experienced by millions of customers. You will regularly work with and learn from the talented members of our multi-disciplinary team of population geneticists, statisticians, computer scientists, and computational biologists to analyze billions of genealogical and genetic records. You will have the challenging role of developing scalable computational approaches to help millions of customers sharing billions of connections understand more about themselves and their family history.

What you will do

  • Develop high-performance, scalable computational methods to analyze genomic data to better infer ancestry and shared relationships

  • Apply data mining, statistics, and/or machine learning when appropriate to refine and improve methods

  • Collaborate with other scientists and departments to leverage different expertise to build better products

  • Breakdown and execute high level project goals with small project focused teams

  • Lead and mentor teams of scientists


  • The successful candidate for the position will have a PhD in computer science, computational biology, bioinformatics, biostatistics, mathematics, statistics, statistical genetics, population genetics, or a related field.
  • Must have experience using or developing high-performance, scalable computational methods to analyze genomic data. Hands-on experience working with very large genomic datasets is ideal.

  • Proficiency in programming and can implement or validate new approaches efficiently. Experience in Python, C/C++, or Java is desired.

  • Minimum 2 years of work experience as an independent scientist is desired.

  • Working knowledge of statistical or machine learning approaches. Experience analyzing genomic or population data is a plus, for example:

    • Knowledge of supervised techniques for classification and assignment or unsupervised learning/clustering techniques, or

    • Knowledge of sequence modeling algorithms (e.g., Markov models, probabilistic context-free grammars), sampling techniques, and expectation-maximization.

  • Experience with distributed computing and big data analysis (e.g., tens of billions of records) is a plus.

    • Experience could include HPC, Hadoop and/or Spark.

  • Strong organizational and interpersonal skills will be needed in our collaborative and fast-paced team.

  • Excellent verbal and written communication skills are required.

  • Exposure to leading and mentoring teams of junior scientists is a plus.




Additional Information

Ancestry is a profitable, growing company with a positive, high-energy environment. Together, our dedicated teams are harnessing the power of technology and using it to simplify the way people connect with their families and their unique legacies. Our work environment is fast-paced and challenging, but also extremely exciting. You’ll work with a team of passionate, engaged individuals. We offer excellent benefits and a competitive compensation package. For additional information, regarding our benefits and career information, please visit our website at

Ancestry is not accepting unsolicited assistance from search firms for this employment opportunity. All resumes submitted by search firms to any employee at Ancestry via-email, the Internet or in any form and/or method without a valid written search agreement in place for this position will be deemed the sole property of Ancestry. No fee will be paid in the event the candidate is hired by Ancestry as a result of the referral or through other means.

Ancestry is an Equal Opportunity Employer that makes employment decisions without regard to race, color, religious creed (including religious dress and grooming practices), national origin, ancestry, sex (including pregnancy, childbirth, breastfeeding, and medical conditions related thereto), sexual orientation, gender, gender identity and expression, age (40 and older), mental or physical disability (including HIV and AIDS), medical condition (cancer and genetic characteristics), veteran status, citizenship, marital status, genetic information, or any other basis that is prohibited by applicable law.   The Company also makes reasonable accommodations to applicants or employees with qualifying disabilities who request them and who otherwise meet the requirements of applicable law.  If you would like to request an accommodation during the application process, please contact our Director of Recruiting.  

All job offers are contingent on a background check screen that complies with applicable law.  For San Francisco office candidates, Ancestry will consider for employment qualified applicants with criminal histories in a manner consistent with the requirements of San Francisco's Fair Chance Ordinance.